Uric acid
Uric acid is an organic component of urine and the final product of decomposition of purin substances, which are an integral part of the protein in the nucleus of human and animal cells. The largest part of the uric acid is excreted to the kidneys and by kidneys in urine, a small part is excreted through the intestines, although it is a waste product, normally it is found in the blood a 34 mg of uric acid. When there is disorder in degradation of purin own cells or substances of food intake, it increases the amount of uric acid. How the disease a uric acid is not secreted in normal quantity out of the organism, it leads to its retention in the blood.
Deposition of uric acid crystals in joints
With more than 50% of the patients and in which there are still no signs of illness, crystals of uric acid are deposited in some parts of the body. Except in the kidneys, uric acid crystals are deposited under the skin and on the joints at different locations in the body. As the uric acid crystals are deposited very slowly in one place, deposits grow slowly and often become visible and painful after 10 years and over. How slow the process of deposition of uric acid crystals is seen by the fact that the total amount of these crystals, which are deposed over the years, is usually not more than 35 grams. Only at a very increased amount of uric acid in the blood, which has already caused damage in kidneys, crystal deposits in joints are formed quickly.
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