
Medical treatment significantly changed in the last 10-15 years. Since the pathological process is taking place at several levels, using the "combination therapy" (a combination of several drugs) we try to act on different mechanisms of disease. Since the destructive changes of joint develop very early, especially in the first 2 years of illness, we are trying to suppress inflammation and prevent further development of the damage with a specific therapy. Today treatment is based on the setting diagnosis as earlier as possible and the beginning of combination therapy with several basic drugs from the beginning of the disease. "Gold standard" in the treatment of RA today is methotrexate, immunosuppressive drugs that is given in weekly doses. For the purpose of repressing inflammatory activities from the beginning of the disease is applied low-dose of corticosteroids. Successfully are used drugs like Sulfasalazine and resochina, and lesser gold salts. Application also have anti-rheumatics non-steroidal (NSAID), which have primarily analgesic effect, but also the anti-inflammatory effect. Today there are already on the market NSAIDs with fewer side effects in the area of digestive system, and with the same anti-inflammatory efficacy - koksibi or COX-2 inhibitors. Today they are registered or pending registration of new drugs called biologic agents.
In the treatment an imperative place has and a method of physical therapy and kinesiotherapy (therapeutic exercises) with the aim of preserving the functional abilities of patients in all stages of the disease. Such treatment should be strictly individual, respecting the various stages of the disease, existing joint damage, age and sex of patients and general cardiovascular changes.
In the treatment an imperative place has and a method of physical therapy and kinesiotherapy (therapeutic exercises) with the aim of preserving the functional abilities of patients in all stages of the disease. Such treatment should be strictly individual, respecting the various stages of the disease, existing joint damage, age and sex of patients and general cardiovascular changes.
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